Bioreactors such as the INFORS HT Labfors 5 are used in the pharmaceutical industry for the incubation of cell cultures and microorganisms, for example in the production of antibiotics. The INFORS HT Labfors 5 can be used in four different configurations for cultivating microorganisms, cell cultures, phototrophic organisms and for carrying out various types of enzymatic hydrolysis and fermentation. Thanks to its modular design, it can be adapted to a wide variety of processes, for example by additionally gassing the culture media.
However, in order to prevent contamination by foreign germs before inoculating the culture vessels, the corresponding vessels and important accessory elements of the fermenter must first be reliably sterilized. This is where Systec's laboratory autoclaves come into play: they are able to safely kill germs and bacteria with highly heated steam under high pressure to ensure the hygienic production of bacterial cultures.
At Analytica 2020, Systec will be demonstrating on site how the INFORS HT Labfors 5 systems and the Systec V-series autoclaves work together and make the sterilization process particularly straightforward. This is because the INFORS HT Labfors 5 culture vessel, together with all accessories (pumps etc.), can simply be placed in the Systec V-series stand-alone autoclave (with corresponding volume) using a lifting device with swivel arm and a fermenter chain and sterilized there. The water vapor used in Systec V-series devices also safely penetrates complex-shaped objects such as pump tubes. This ensures reliable, reproducible and validatable sterilization of the critical elements of the INFORS HT Labfors 5.
Systec accompanies the entire sterilization process and ensures reproducibility and validatable results, which can optionally be documented fully digitally.
Image: @Infors HT